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Basilea secures $30 million BARDA funding to advance Phase 3 development of its antifungal fosmanogepix

Executive summary: Basilea received a $30 million funding award from BARDA to advance Phase 3 development of its antifungal fosmanogepix. The award provides non‑dilutive capital for costly Phase 3 trials and supports the development of a needed antifungal amid rising resistant infections.

Who is involved: Basilea Pharmaceuticals; Biomedical Advanced Research and Development Authority (BARDA), part of the U.S. Department of Health and Human Services.

Likely next: Basilea will use the funds to progress fosmanogepix through Phase 3 trials, with potential regulatory milestones and additional BARDA payments contingent on trial progress.

Basilea announced that it has received a $30 million tranche under its existing agreement with the Biomedical Advanced Research and Development Authority (BARDA). The funds are earmarked for moving the novel antifungal agent fosmanogepix into Phase 3 clinical trials, addressing a growing need for new treatments against drug‑resistant fungal infections. This non‑dilutive financing reduces Basilea’s R&D cash‑burn and signals continued U.S. government support for antimicrobial countermeasure development.

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