MarketsandMarkets projects oligonucleotide synthesis market to more than double by 2031, driven by expanding therapeutic and diagnostic applications
Executive summary: MarketsandMarkets released a forecast that the global oligonucleotide synthesis market will reach USD 32.72 billion by 2031, up from USD 14.64 billion in 2026. The projected doubling of market size signals rising capital investment in oligo‑based therapeutics and diagnostics, affecting suppliers, biotech firms and healthcare spending.
Who is involved: MarketsandMarkets (analyst firm), oligonucleotide synthesis providers (e.g., IDT, Twist Bioscience, Thermo Fisher), and end‑users in pharma and diagnostics.
Likely next: Companies will likely announce capacity expansions and new GMP‑grade facilities to meet the anticipated demand, with quarterly updates expected throughout 2027‑2028.
The report estimates the market will grow from USD 14.64 billion in 2026 to USD 32.72 billion in 2031, a CAGR of 17.4 %. This expansion reflects increased demand for oligos in mRNA‑based vaccines, gene therapies and molecular diagnostics. The forecast assumes continued adoption of synthetic biology tools and a stable regulatory environment for oligonucleotide drugs.
Timeline
- — Oligonucleotide Synthesis Market worth $32.72 billion by 2031 - Exclusive Report by MarketsandMarkets™ (PR Newswire)
- — 3D Printing Market worth $31.77 billion by 2032 - Exclusive Report by MarketsandMarkets™ (PR Newswire)
Analysis — what this means
Likely next events
- 2026 Q4: market size projected to reach ~USD 16.2 billion (based on 17.4 % CAGR).
- 2027: expected to exceed USD 19.0 billion.
- 2028: projected to surpass USD 22.5 billion.
Sectors affected
- oligonucleotide synthesis
- biotech reagents
- molecular diagnostics
- gene therapy manufacturing
Key entities
Sources
- Oligonucleotide Synthesis Market worth $32.72 billion by 2031 - Exclusive Report by MarketsandMarkets™ — PR Newswire
- 3D Printing Market worth $31.77 billion by 2032 - Exclusive Report by MarketsandMarkets™ — PR Newswire
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